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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f32949a5f6278db2ae17f155398e00db6593016bc181c44aa0a2dc2ceb84c352' 
  AND token = 'VRe57Mg/yAg3GnSH/nqdoy+2oq4M8/P0D53E51NRBZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}