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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d7d4bb7ec876d8392cdb60c2ea8cd785b5f6e2e00415731a77e532138b819e5' 
  AND token = '2XnHgxe3H1wTeu2S26bOP6EGtDYcsVKCNph2nISpqOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}