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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '417c651eb13ae7c8a2eb6c32a8147037340872b925f81f0535bee11f31747afe' 
  AND token = 'Z8JBaf1QGjdKZ5qV7uM2TYuca+eW9H8Yw1rpwbAelKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}