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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500314923186148dbefc96b0ee28afae5ae6914498cc8d5988ed1102903d3560' 
  AND token = 'HNYo/SLqEbGt1WMnBZ2m5Aw6/5IGILJIKSDE42j+ZSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}