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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06b8d41ed9e77ba24cb65d8f5b2906e1cd6b23801fd009606408d4faff0ab08c' 
  AND token = 'fV2v406/h/3Y2TA6Sl1lkFQT2OSsNttcJ9pxXRAVvOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}