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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd81b548fdbfeccd65039652cba3f04ef2e4426b4d59e89ce40f3730712d7530c' 
  AND token = 'O82bJNM19S//45SlypFJjmDf80uj3gDQRlwC7pTP5yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}