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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8562a4f86c3e44cc7be313b5ce3683694a70b9a2064d6e3233a77488a018b607' 
  AND token = 'NUc/DD2cBfudGBDrFsQzbg//Q3rSk5QIicvOM9eif0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}