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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2113d7b8bfc53a1b1728421fa437f42682a5840b810669816810be2319309fd1' 
  AND token = 'aYZfhq+1Qky8gLtnZ8+OWGBHNbPq+QsAuHUQNGrc8Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}