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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b3e773de15be76aa11c544fff09c6116772c2d3382e3666fbd7b6dc9447af8' 
  AND token = 'VAEb7UYR9i4PTmiTofL7hmX/QrIIOc7xdujigv4Mw44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}