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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '618745f27f7cf1328ace9b27c2f6528ae60253045df1da6650e46b3415e5ddb4' 
  AND token = 't4byd17Nj6qv7xAzycnAArsXXRwvNfOfn+HRZZ6PXA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}