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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13fef6f43fc5235c8b86e85d18c90f676e7510c6159f40905e6bbe0fde0b9ef' 
  AND token = 'noTvsewylBz7cJkZuBkFwiNjr6bv8rlKhmVzL2y5Tr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}