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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a37b722d6ade1a12753420a57742909687968b1a5dda68f77248362fb61f366' 
  AND token = 'e/iYmZ7xOemj9x2i9KfZW/SgZNpthn9DJ88kCYEo/Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}