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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b414f78a01af947218a5df7c6c46aac3337db59d163fd3c44d711275c6b4b64b' 
  AND token = 'HFNd9QhVbz02lacd5o5hHj8BQGakqzrnekqmZdl115c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}