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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa71be83018e10d8cd97425596f6fdbea4d5b68f05fa2870ecf748c2010d2257' 
  AND token = 'jL0fZc6lOXRmh0NNGG61urSQfClKW8Or3aBJWQcOCFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}