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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eecbd512dd35eac561d1e2e3ab9f3870100cba9e8533724e7438807d2b59b5fb' 
  AND token = 'LQI/zs805cQxSKZoM7OsOvHTzFC83G9ii2W6UCqIotc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}