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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78704b6def3ac0265a3328e420654a9c50db24d0780631727860c7c265d521b' 
  AND token = 'gdmhVzE2+tFP4LvVbPHs4KNp92IakO1HNFH7ku47sNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}