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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5688249ec6f18cbb26f586354986a2de4ce7f973b04bff72bc7c307129bf6ab' 
  AND token = 'SkWOQoAFjkxVY6P88tVxRz/v7qG1l0gn5iIu39GS418=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}