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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5101955af3bd570d3228681ae3ebdcb50df0c1d2f48b56fe43fc45385ceb26b4' 
  AND token = 'IvfqdMZzlnP16/2xxzVLDTAA+6dgZGVfnOeyE74oFd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}