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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79152f1ce2409003e1cbd48ff680b962c153fb51b191414d9a3962f54121b1c5' 
  AND token = '/NVn9dshWG2HeMUgmYiSDyNGna7GhmB8070gp7BBuDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}