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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f80a829a8c68955290e653879f31857e0209d16d8fd623801108df4e8613c08' 
  AND token = 'byhf9+XUh0n+HqJ48kXiWNXWXFPW/6YgLFfxeYVBT00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}