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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cf8d5e3eca462abfc9a49721fd90eabd3950c41e4e5a0a7f3b27ec5cb9e52b9' 
  AND token = 'FppQ8b5J39yfrUwS/UAlJXEI3DN2VieEhF9dTH9RnCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}