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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb8045171f9df6d082ec6533bc4c43f88ba9f62851c37df443d6a1ec5a61781' 
  AND token = 'o9mvagDRoAM7Q6jB0G8UileinBpVSQMRo3djnaMhiVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}