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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e87ae7b66af050c9fa7da533eb864794c0909f10c7e8a2b0c96285abeab4109' 
  AND token = 'Syq3TjgWAI2zLMAoKXbrq9Y2nKTtlStxX4KiNggV1Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}