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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd72db86b32c8566dd3c31e38cad1cda27a0d05e2a026710103f66c505cb705' 
  AND token = 'xGZ0b+x7is+sGQQtqeMymIaMY1kQWrRc0Lv4PkjWsIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}