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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e111b50ad30c1e257e59e8cbcca7e7f88e3d8b5c7a39cd31acc6309f70217d85' 
  AND token = 'jaOFom5RJWeDcsjwG6sqR7qKX5yfsxHAV+CNWQ2BIxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}