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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d750ced9d4b37e78f2d2e5b51cc51cdda77eaacbe89d3051c2720992ef877a' 
  AND token = 'bUDD8vwdVWV3JPPah93BmTsh6X+kGjYtyfdUlva7ZRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}