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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d280547a928a236a6ecbd2621fad7cb63ab5c5fe4168041cd45b563e18789f0' 
  AND token = 'h7Jgh+zLLi/w03EXy2trwYaYixRShbFxbdyn6AGU7y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}