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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c50128eac78ab8f21a63b6b96425da11779305f07fcd4f8c202cbb0f74e11f' 
  AND token = '6+ukf9iwRkx52Uv0UQ9xwXFIKgdPgTSSyS5sBkMa8s4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}