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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6ecdc96bf0c605e25c021cbe483a059bfd1dfc5709d2fb7f600c161409ab438' 
  AND token = '5S5kpROkQq9nTbSfbi84jYeHO6PhkM2+0EYM/xnyvY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}