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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2ed546619f4c8da3ad721b97d40ee2d1202a787662dee879c16bd3b1ab0cd8' 
  AND token = 'Uy68lsMyHTC1qPSqBnhGpBowtwOmJWW/kKmswgX0uYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}