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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78416a8120bbf9df78024b82f5578e45aaed40a76bc9dba96cbc0215635e9c5' 
  AND token = 'Ub2P51aR9mVPLdZddd7SMGQlRmTirX4yGWdQKZPodA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}