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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74a0b39989f59053cf9f9b0ad57f6af5749b738a057d8cdc39db30b4b95c7b20' 
  AND token = 'aZD8mw58g/uIVPT7Guz9ZMvGxERba3cfkBHKWAJajrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}