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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7183156f8ad9d3a0b26c82b347bb0458da986fcd3bcc3de20d966bdf916048dd' 
  AND token = '+xxMDZhi4M3f7fD9TrHxHYf3Dd5XpmMxv/cFKuaZp0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}