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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81add22c62b3c89f33256a3ded09bf6c8a1e83af224962959db78abf43f00108' 
  AND token = '4wGdDGdFuYtY86TLpZ1sWY0qn8lTXRZaE/1jDCtRnqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}