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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb8996f5158069459f961763a2cf0c3271889aa77386351720b9b046346613c9' 
  AND token = 'tfCbGbDXKZBmdeKz8PcG3cjw6dEpZ14i98GclETKVRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}