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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a712dfe1831355a4bcc9048633eb0d36a47c75fc5ffd20e50c56207c68da2a0' 
  AND token = 'l5hgqKIrNmlIRNaG2L46sTfPagx/rrWN7cKlOcEvoUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}