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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4a03ec0a9f969f950947fcb5ce6a4ded79a428dfa27367ee1d13efeaa1433c' 
  AND token = 'n6fR5dUB+4xy43NXv0dM1l6Jy+HPl6g9dBsPNIOredI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}