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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def782179db4a18cd91aff97418b40e3cf973dcb7ac66442fbc61d8a6547f7ff' 
  AND token = 'SYyQ6TyyW6Wun5q4/ULmeJAgbVkWP61b2oobcZ88UF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}