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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6f20a87933301169f39b047eca3e652fa92bca1c422cb0ea31e2544026aa79' 
  AND token = 'jgqZtL6gBzt0sLxtCtH7/FOrM3c7DzzWz9Qy4HRgLP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}