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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eb1fd24078b7b2bc2b4fe1e073121038b220a821b926f5871e9000839a63d02' 
  AND token = '/Wwgh5hMP67439o/PzauTfzbS1w1Ci3UZ9hLUR43IXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}