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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10aa3f68fa4a026395e3757a653bc32e8c253750d004c461beb780cbd7887c32' 
  AND token = 'dItlv6VN/02Bv6MuhB0BQC4wgdh7JE/q/suTh+3/q7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}