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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e19e37a43e2eca9fcc3b27fde900b7d9979ab70b8c2b787337fef1380a368e4' 
  AND token = 'ChEmATGy90fPhMcMpcRjDaH4mKiqlK+I/HMJ8nQoQNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}