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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bb0389e0a301a1602d78231f626f1209a8a6deb4e9b5b0ce5946f482de0a2a' 
  AND token = 'BqPxj35cQCr0r5qE43l8IuLAqY3ErtQgqrtY2zJxkyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}