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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343a6f6c977fd67b4e5ba5808b22a407f2c9b2a1739e03d7052a20afc1bfb0b0' 
  AND token = 'pS3z7fzRnuqHIcsN3B4uXIG6Ggp7GZ0DUqhw3Vr053o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}