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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6589daec1ba270a8bee2a40a3fbd6e967288940b4d9e59d8a4152085fce2f4ba' 
  AND token = 'pNkw53bD+V7mkbhp9jTjgT4AEK6LgQMF5rpJfdP1Zvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}