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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a20ffd998f01c3026e5402b197f74d03e4e216be95ab21dbcc87a7049577293' 
  AND token = 'E4Qh7XXg8kMJHcxza58YS34rtAyTs2E1UhL4W9XaLQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}