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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ddc2ea69bf80c584e59b320724c7699756de8432034e5b277b98864543138a' 
  AND token = '9QGAiVxrXLldPf4RywT7HS9hpp/7VP5XPIACvYYxD2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}