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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f791c847293c786d3666d239ccba95093f8da2a2814e1bf22576311a963ac4d' 
  AND token = '0MxOSLF3JVkbVISHbXP53rd8bCPPGGMDisYHF4wsHHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}