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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f7d1afff7c80179a2c215ea17463abb600a91666e2953690eec887424ac711' 
  AND token = 'DC3b9TEVDs9Pi0WueAkIxAX9IzH3vDpwjmeFn+IE7Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}