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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00ecf5df42ad253ef9db1d76594f6091c4649b2d6d8272bc5686885054a483b' 
  AND token = 'pf059X3SpM9Upwe7/TgC4wvpr1tS94sDCtsW5bHz55E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}